JIANGXI XIERKANGTAI PHARMACEUTICAL CO., LTD.  

Product Name: LOPERAMIDE CAPSULE 2MG Model NO.: 2mg Pharmaceutical Technology: Chemical Synthesis Type: Biological Products Shape: Capsules State: Solid Suitable for: Adult Usage Mode: For oral administration Application: Internal Medicine Transport Package: 10's/Blister, Box, Carton Specification: 2mg Origin: China HS Code: 3004909099 Product Description COMPOSITION 2mg loperamide hydrochloride per capsulePHARMACOLOGICAL CLASSIFICATION Medicines acting on gastro-intestinal tract. Antidiarrhoeals.PHARMACOLOGICALACTION PERATOR CAPS inhibits hypermotility by direct action on the bowel wall. Its inhibition of peristalsis isthe result of decreasing the activity of both the longitudinal museles (preparatory and reflex phases) andthe circular muscles (reflex phase).PERATOR CAPS normalizes the stool in both acute and chronic diarrhoea.PERATOR CAPS is incompletely absorbed from the gut, and it is almost completely metabolized in theliver where it is conjugated and excreted via the bile.PERATOR CAPS is mainly eliminated via the faeces.INDICATIONS Adults and children 6 years and older: PERATOR CAPS is indicated for the control and symptomaticrelief of acute and chronic nonspecific diarrhoea and inhibition of peristalsis and slowing of intestinaltransit time in patients with ileostomies, colostomies and other intestinal resections.Children below 6 years of age: PERATOR CAPS is indicated for inhibition of peristalsis and slowingintestinal transit time.CONTRA-INDICATIONS PERATOR CAPS is contra-indicated in patients with a known hypersensitivity to the medicine.PERATOR CAPS is contra-indicated in infants under 24 months of age.Since treatment of diarrhoea with PERATOR CAPS is only symptomatic, diarrhoea should be treatedcausally, whenever causal treatment is available. PERATOR CAPS should not be used as the primarytherapy in acute dysentery, which is characterised by blood in stools and high fever. PERATOR CAPS must not be used in patients with acute ulcerative colitis or pseudomembranous colitisassociated with broad-spectrum antibiotics. In general, PERATOR CAPS should not be used wheninhibition of peristalsis is to be avoided and must be discontinued promptly if constipation, abdominaldistension or subileus develop. Loperamide administration may precipitate toxic megacolon in patientswith inflammatory bowel disease.The safety of use during pregnancy and lactation has not been established.DOSAGE AND DIRECTIONS FOR USE PERATOR CAPS should not be used in infants under 2 years. The capsules, however, are not suited forchildren under 6 years of age.Acute non-specific diarrhoea. For adults and children of 6years and older: 2 capsules (adults)or I capsule(children)as an initial dosefollowed by I capsule after each subsequent loose stool..